Already in 1903 The Austrian researcher Schein (think he was Austrian at least) described correctly that MPB was caused by skull expansion and the resulting galea/skin tension, and eventually reduced circulation to the scalp region above the galea. (1) This resulted much later in the attempts by Kessler and Ponten in 1963 to try and relieve that galea tension by performing "frontalotomy" and "galetomy" respectively in bald men. Both procedures where meant to relive the galea tension and restore normal circulation.
Well, they both failed to restore hair growth, and we now know why; In children with the congenital condition sagittal synostosis, (enlarged/misshaped skull) a similar pattern to AGA emerges in some cases. (2) They develop AGA that is reversed post surgery. In bald adults that have scalp reductions performed however, the same lack of results as in the above mentioned procedures are seemingly seen. The simple reason is that the chronic scalp tension caused fundamentally by skull expansion results in gradual and progressive tissue fibrosis. (3) Once there is too much extracellular matrix formed, eliminating the more "upstream" cause won't help. We have to reverse the fibrosis. (In children with SS there has not been enough time then for fibrosis to settle in.) Anyway, I refer to my previous posts for a more in-depth breakdown of the etiology of MPB also. (4)
I get frustrated and pissed at this stuff tbh. Analogous to this story, in 1917 Rebecca Oppenheimer (of the same Austrian-Hungarian culture as Schein) released a low-carb/paleo type cookbook intended for diabetes sufferers. (5) Well, she was right basically, and that was over 100 years back. It took about a 100 years for those ideas to be rediscovered, and still most MD's will not tell diabetes type 2 patients to eliminate refined carbs etc. The conclusion is that science in 2022 is in the dark ages once more, as has been the norm for most of the history of civilization. In fact I think that this period might be the darkest ever. It's up to the few that still are curious about nature and the objective reality of things to figure this out, and we'll have all the powers that be against us in that quest the way things are currently.
Share this post
The real cause of MPB was know already 120 years ago!
Share this post
Already in 1903 The Austrian researcher Schein (think he was Austrian at least) described correctly that MPB was caused by skull expansion and the resulting galea/skin tension, and eventually reduced circulation to the scalp region above the galea. (1) This resulted much later in the attempts by Kessler and Ponten in 1963 to try and relieve that galea tension by performing "frontalotomy" and "galetomy" respectively in bald men. Both procedures where meant to relive the galea tension and restore normal circulation.
Well, they both failed to restore hair growth, and we now know why; In children with the congenital condition sagittal synostosis, (enlarged/misshaped skull) a similar pattern to AGA emerges in some cases. (2) They develop AGA that is reversed post surgery. In bald adults that have scalp reductions performed however, the same lack of results as in the above mentioned procedures are seemingly seen. The simple reason is that the chronic scalp tension caused fundamentally by skull expansion results in gradual and progressive tissue fibrosis. (3) Once there is too much extracellular matrix formed, eliminating the more "upstream" cause won't help. We have to reverse the fibrosis. (In children with SS there has not been enough time then for fibrosis to settle in.) Anyway, I refer to my previous posts for a more in-depth breakdown of the etiology of MPB also. (4)
I get frustrated and pissed at this stuff tbh. Analogous to this story, in 1917 Rebecca Oppenheimer (of the same Austrian-Hungarian culture as Schein) released a low-carb/paleo type cookbook intended for diabetes sufferers. (5) Well, she was right basically, and that was over 100 years back. It took about a 100 years for those ideas to be rediscovered, and still most MD's will not tell diabetes type 2 patients to eliminate refined carbs etc. The conclusion is that science in 2022 is in the dark ages once more, as has been the norm for most of the history of civilization. In fact I think that this period might be the darkest ever. It's up to the few that still are curious about nature and the objective reality of things to figure this out, and we'll have all the powers that be against us in that quest the way things are currently.